1. #1
    Unregistered

    Latest syllabus of Life Science for CSIR?

    can u send me the latest syllabi for CSIR exam regarding lifesciences?
    actually i am in urgent need for it.

  2. #2
    sumit pandey Array
    Join Date
    Dec 2011
    Posts
    340

    Re: Latest syllabus of Life Science for CSIR?

    hi,

    The Joint CSIR-UGC JRF/LS (NET) Examination shall comprise 2 papers:


    PAPER I: duration: 2 ½ hours and maximum of 200 marks. 2 marks each question. (252752)

    Part -A: 40 General Science questions, attempt any 25 questions.

    Part -B: 100 questions, attempt any 75 questions.

    PAPER II: 2 ½ hours duration and shall have a maximum of 200 marks (2011512)

    This Paper shall consist of 39-45 short answer type questions requiring descriptive answers. Answer each question, on one page.

    There shall be one compulsory question of twenty Marks. In addition to the compulsory question, the candidate is required to answer a maximum of 15 questions of twelve marks each.



    SYLLABUS FOR PAPER I AND II



    1. MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY


    1. Structure of atoms, molecules and chemical bonds.
    1. Composition, structure & function of biomolecules (carbohydrates, lipids, proteins, N.Acids and vitamins).
    1. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding, hydrophobic interaction, etc.).
    1. Principles of biophysical chemistry (pH, buffer, reaction kinetics, thermodynamics, colligative properties).
    1. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.
    1. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.
    1. Conformation of proteins (Ramachandran plot, 20, 30 & 40 structures; domains; motif and folds).
    1. Conformation of nucleic acids (A-, B-, Z-, DNA), t-RNA, micro-RNA).
    1. Stability of protein and nucleic acid structures.
    1. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.


    2. CELLULAR ORGANIZATION


    1. Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting & regulation of intracellular transport, electrical properties of membranes.
    1. Structural organization and function of intracellular organelles: Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, ER , peroxisomes, plastids, vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility.
    1. Organization of genes and chromosomes: Operon, interrupted genes, gene families, structure of chromatin and chromosomes, unique and repetitive DNA, heterochromatin, euchromatin, transposons.
    1. Cell division & cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle.
    1. Microbial Physiology: Growth, yield & characteristics, strategies of cell division, stress response.
    3. FUNDAMENTAL PROCESSES
    1. DNA replication, repair and recombination: Unit of replication, enzymes involved, replication origin and replication fork, fidelity of replication, extrachromosomal replicons, and DNA damage and repair mechanisms.
    1. RNA synthesis and processing: Transcription factors and machinery, formation of initiation complex, transcription activators and repressors, RNA polymerases, capping, elongation & termination, RNA processing, RNA editing, splicing, polyadenylation, structure and function of different types of RNA, RNA transport.
    1. Protein synthesis and processing: Ribosome, formation of initiation complex, initiation factors and their regulation, elongation and elongation factors, termination, genetic code, aminoacylation of tRNA, tRNA-identity, aminoacyl tRNA synthetase, translational proof-reading, translational inhibitors, post- translational modification of proteins.
    1. Control of gene expression at transcription and translation level: Regulation of phages, viruses, prokaryotic and eukaryotic gene expression, role of chromatin in regulating gene expression and gene silencing.


    4. CELL COMMUNICATION & CELL SIGNALING


    1. Host parasite interaction: Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells.
    1. Cell signaling: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component signaling systems, bacterial chemotaxis and quorum sensing.
    1. Cellular communication: Regulation of hema topoiesis, general principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins, neurotransmission and its regulation.
    1. Cancer: Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.
    1. Innate and adaptive immune system: Cells & molecules involved in innate and adaptive immunity, antigens, antigenicity and immunogenicity. B and T cell epitopes, structure & function of antibody molecules, generation of antibody diversity, monoclonal antibodies, antibody engineering, antigen-antibody interactions, MHC molecules, antigen processing & presentation, activation and differentiation of B & T cells, B and T cell receptors, humoral & cell-mediated immune responses, primary & secondary immune modulation, the complement system, Toll-like receptors, cell-mediated effector functions, inflammation, hypersensitivity & autoimmunity, immune response during bacterial (tuberculosis), parasitic (malaria) & viral (HIV) infections, congenital and acquired immunodeficiencies, vaccines.


    5. DEVELOPMENTAL BIOLOGY


    1. Basic concepts of development: Potency, commitment, specification, induction, competence, determination & differentiation; morphogenetic gradients; cell fate & cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; imprinting; mutants & transgenics in analysis of development.
    1. Gametogenesis, fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animals; embryo sac development & double fertilization in plants; zygote formation, cleavage, blastula formation, embryonic fields, gastrulation & formation of germ layers in animals; embryogenesis, establishment of symmetry in plants; seed formation & germination.
    1. Morphogenesis & organogenesis in animals: Cell aggregation & differentiation in Dictyostelium; axes and pattern formation in Drosophila, amphibia and chick; organogenesis – vulva formation in Caenorhabditis elegans; eye lens induction, limb development & regeneration in vertebrates; differentiation of neurons, post embryonic development-larval formation, metamorphosis; environmental regulation of normal development; sex determination.
    1. Morphogenesis and organogenesis in plants: Organization of shoot and root apical meristem; shoot and root development; leaf development and phyllotaxy; transition to flowering, floral meristems and floral development in Arabidopsis and Antirrhinum.
    1. Programmed cell death, aging and senescence.
    6. SYSTEM PHYSIOLOGY PLANT


    1. Photosynthesis: LH complexes; mechanisms of ETC; photoprotective mechanisms; CO2 fixation-C3, C4 CAM pathways.
    1. Respiration & photorespiration: TCA cycle; plant mitochondrial ET & ATP synthesis; alternate oxidase; photorespiration.
    1. Nitrogen metabolism: Nitrate and ammonium assimilation; amino acid biosynthesis.
    1. Plant hormones: Biosynthesis, storage, breakdown and transport; physiological effects and mechanisms of action.
    1. Sensory photobiology: Structure, function & mechanisms of action of phytochromes, cryptochromes & phototropins; stomatal movement; photoperiodism and biological clocks.
    1. Solute transport & photoassimilate translocation: Uptake, transport & translocation of water, ions, solutes & macromolecules from soil, through cells, across membranes, through xylem & phloem; transpiration; mechanisms of loading & unloading of photoassimilates.
    1. Secondary metabolites: Biosynthesis of terpenes, phenols and nitrogenous compounds and their roles.
    1. Stress physiology: Responses of plants to biotic (pathogen and insects) and abiotic (water, temperature and salt) stresses; mechanisms of resistance to biotic stress and tolerance to abiotic stress


    7. SYSTEM PHYSIOLOGY ANIMAL


    1. Blood and circulation: Blood corpuscles, haemopoiesis and formed elements, plasma function, blood volume, blood volume regulation, blood groups, haemoglobin, immunity, haemostasis.
    1. Cardiovascular System: Comparative anatomy of heart structure, myogenic heart, specialized tissue, ECG – its principle and significance, cardiac cycle, heart as a pump, blood pressure, neural and chemical regulation of all above.
    1. Respiratory system: Comparison of respiration in different species, anatomical considerations, transport of gases, exchange of gases, waste elimination, neural and chemical regulation of respiration.
    1. Nervous system: Neurons, action potential, gross neuroanatomy of the brain and spinal cord, central and peripheral nervous system, neural control of muscle tone and posture.
    1. Sense organs: Vision, hearing and tactile response.
    1. Excretory system: Comparative physiology of excretion, kidney, urine formation, urine concentration, waste elimination, micturition, regulation of water balance, blood volume, blood pressure, electrolyte balance, acid-base balance.
    1. Thermoregulation: Comfort zone, body temperature – physical, chemical, neural regulation, acclimatization.
    1. Stress and adaptation
    1. Digestive system: Digestion, absorption, energy balance, BMR.
    Best of Luck

  3. #3
    KamatchiDeviK Array
    Join Date
    Dec 2011
    Location
    Trichy
    Posts
    212

    Re: Latest syllabus of Life Science for CSIR?

    Hi Friend,

    I have attached the Life Science Syllabus for CSIR with this message . Plz find it.

    ALL THE VERY BEST for future.....
    Attached Files

  4. #4
    King Array
    Join Date
    Dec 2011
    Location
    Hyderabad
    Posts
    544

    Lightbulb Re: Latest syllabus of Life Science for CSIR?

    Hello Dear,
    There will be a joint C.S.I.R-U.G.C JRF/LS(NET) Examination which will consist of 2 papers.Paper 1 is of 2 hours 30 minutes duration and will consist of 200 marks.Each question will carry 2 marks.In Paper-1 there are two parts.PART-A will consist of 40 questions from General Science and you have two attempt any 25 questions.While Part-B will consist of 100 questions out of which you have to attempt 75 questions.
    In Paper-2 there will total 200 marks of 2 hours and 30 minutes duration.This paper will consist of 39 to 45 short answer type questions which requires descriptive answers.There will be one compulsory question of 20 marks.

    I am attaching a file which consists of the complete syllabus for Paper-1 and Paper-2 of Life Science for C.S.I.R.

    I hope this will help you.
    Good Luck for your exam.
    Prepare nicely and do well.
    Attached Files

  5. #5
    dinesh5nov_1985 Array
    Join Date
    Jan 2012
    Posts
    394

    Re: Latest syllabus of Life Science for CSIR?

    Hi
    CSIR-NET: national eligibility test which is conduct University grant commission twice in year

    1. Moleucules and their interaction relavent to biology

    2. Cellular organization
    Membrane structure and function
    Structural Organisation and function of intracellular organelles
    organization of genes and chromosomes
    Cell division and cell cycle
    Microbial Physiology

    3. Fundamental Process
    DNA replication, repair and recombination
    RNA synthesis and processing
    Protein synthesis and processing
    control of gene expression at transcription and translation level

    4.Cell Communication and Cell Signaling
    Host parasite Interaction
    Cell signaling
    Cellular communication
    Cancer
    Innate and adaptive immune system

    5. Development Biology
    basic concepts of development
    Gametogenesis, fertallization and early development
    morphogenesis and organogenesis in animals
    Morphogenesis and Organogenesis in plants

    6. System physiology-Plant
    Photosynthesis
    Respiration and Photorespiration
    Nitrogen Metabolism
    Plant Hormones
    Sensory Photobiology
    solute transport and photoassimilate translocation
    stree physiology

    7. System Physiology Animal
    8. Inheritance biology
    9. Diversity of life forms
    10 Ecological Principles
    11. Evolution and Behaviour
    12.Applied Biology
    13. Methods in Biology

    best of luck

  6. #6
    venkataprakash Array
    Join Date
    Dec 2011
    Location
    Chennai
    Posts
    249

    Re: Latest syllabus of Life Science for CSIR?

    Life Science Syllabus :-

    1)Molecules and their Interaction Relevant to Biology
    2)Cellular Organisation
    3)Fundamental Process
    4)Cell Communication and Cell Signaling
    5)Development Biology
    6)System Psychology - Plant
    7)System Psychology - Animal
    8)Interitance Biology
    9)Diversity of Life forms
    10)Ecological Principles
    11)Evolution and behavior
    12)Applied Biology
    13)Method in Biology


    Exam Pattern of Life Science :-



    Important dates for CSIR :-

    >>Date of Sale of Application forms(offline) :- 21.02.12
    >>Start date of online Application :- 21.02.12
    >>Date of examination :- 17.06.12

    Education Qualification :-

    The candidate need to completed M.Sc or equivalent qualification from a recognized University and the candidate must secure at least 55% aggregate marks in their examination and 50% aggregate marks for reserved categories.Those in the final year of degree course may also eligible to apply for CSIR examination.

    The candidate age should be between 19 years and 28 years at the time of appearing for this examination and relaxation is given to the reserved categories.

    More details,Visit the official website :- http://www.csirhrdg.res.in/
    Attached Files

  7. #7
    irasharma Array
    Join Date
    Dec 2011
    Posts
    372

    Re: Latest syllabus of Life Science for CSIR?

    The Joint CSIR-UGC JRF/LS (NET) Examination shall comprise 2 papers:

    [FONT=Times New Roman]SYLLABUS FOR PAPER I AND II[/FONT]
    [FONT=Times New Roman][/FONT]
    [FONT=Times New Roman]1. MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY [/FONT]
    [FONT=Times New Roman][/FONT]
    [FONT=Times New Roman]A. Structure of atoms, molecules and chemical bonds. [/FONT]

    B. Composition, structure & function of biomolecules (carbohydrates, lipids, proteins, N.Acids and vitamins).

    C. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding, hydrophobic interaction, etc.).

    D. Principles of biophysical chemistry (pH, buffer, reaction kinetics, thermodynamics, colligative properties).

    E. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.

    F. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.

    G. Conformation of proteins (Ramachandran plot, 20, 30 & 40 structures; domains; motif and folds).

    H. Conformation of nucleic acids (A-, B-, Z-, DNA), t-RNA, micro-RNA).

    I. Stability of protein and nucleic acid structures.

    J. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.

    2. CELLULAR ORGANIZATION

    A. Membrane structure and function

    B. Structural organization and function of intracellular organelles

    C. Organization of genes and chromosomes

    D. Cell division & cell cycle

    E. Microbial Physiology

    3. FUNDAMENTAL PROCESSES
    A. DNA replication, repair and recombination

    B. RNA synthesis and processing

    C. Protein synthesis and processing

    D. Control of gene expression at transcription and translation level



    4. CELL COMMUNICATION & CELL SIGNALING

    A. Host parasite interaction

    B. Cell signaling

    C. Cellular communication

    D. Cance

    E. Innate and adaptive immune system

    5. DEVELOPMENTAL BIOLOGY

    A. Basic concepts of development

    B. Gametogenesis, fertilization and early development

    C. Morphogenesis & organogenesis in animals.

    D. Morphogenesis and organogenesis in plants

    E. Programmed cell death, aging and senescence.

    6. SYSTEM PHYSIOLOGY PLANT

    A. Photosynthesis

    B. Respiration & photorespiration

    C. Nitrogen metabolism

    D. Plant hormones

    E. Sensory photobiology

    F. Solute transport & photoassimilate translocation

    G. Secondary metabolites

    H. Stress physiology

    7. SYSTEM PHYSIOLOGY ANIMAL

    A. Blood and circulation

    B. Cardiovascular System

    C. Respiratory system

    D. Nervous system

    E. Sense organs

    F. Excretory system

    G. Thermoregulation

    H. Stress and adaptation

    I. Digestive system
    [FONT=Calibri][/FONT]

  8. #8
    archna21 Array
    Join Date
    Feb 2012
    Posts
    473

    Smile Re: Latest syllabus of Life Science for CSIR?

    CSIR Life Science Syllabus for Paper I and II




    > MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY

    * Structure of atoms, molecules and chemical bonds.
    * Composition, structure & function of biomolecules.
    * Stabilizing interactions.
    * Principles of biophysical chemistry.
    * Bioenergetics,glycolysis,oxidative phosphorylation,coupled reaction,group transfer,biological energy transducers.
    * Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.
    * Conformation of proteins.
    * Conformation of nucleic acids.
    * Stability of protein and nucleic acid structures.
    * Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.


    > CELLULAR ORGANIZATION


    * Membrane structure and function
    * Structural organization and function of intracellular organelles
    * Organization of genes and chromosomes
    * Cell division & cell cycle
    * Microbial Physiology


    > FUNDAMENTAL PROCESSES


    * DNA replication, repair and recombination
    * RNA synthesis and processing
    * Protein synthesis and processing
    * Control of gene expression at transcription and translation level


    > CELL COMMUNICATION & CELL SIGNALING


    * Host parasite interaction
    * Cell signaling
    * Cellular communication
    * Cancer
    * Innate and adaptive immune system


    > DEVELOPMENTAL BIOLOGY


    * Basic concepts of development
    * Gametogenesis, fertilization and early development
    * Morphogenesis & organogenesis in animals
    * Morphogenesis and organogenesis in plants
    * Programmed cell death, aging and senescence.


    > SYSTEM PHYSIOLOGY PLANT


    * Photosynthesis
    * Respiration & photorespiration
    * Nitrogen metabolism
    * Plant hormones
    * Sensory photobiology
    * Solute transport & photoassimilate translocation
    * Secondary metabolites
    * Stress physiology


    > SYSTEM PHYSIOLOGY ANIMAL


    * Blood and circulation,
    * Cardiovascular System
    * Respiratory system
    * Nervous system
    * Sense organs
    * Excretory system
    * Thermoregulation
    * Stress and adaptation
    * Digestive system

  9. #9
    S.Narasimha Murthy Array
    Join Date
    Feb 2012
    Location
    Hyderabad
    Posts
    174

    Re: Latest syllabus of Life Science for CSIR?

    Hi Friend,

    I am attaching the latest syllabus of CSIR Life sciences, Please find the attachment below and go through it, download it.

    All the best, have a bright future.
    Attached Files

  10. #10
    sumansin Array
    Join Date
    Feb 2012
    Posts
    359

    Re: Latest syllabus of Life Science for CSIR?

    CSIR net exam held every year two time for jrf and lecturership in month of june and december by UGC

    Aspirant must be post graduate with 55% marks in science stream from recognise university.

    Syllabus for Life Science


    1. MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY
    * Structure of atoms, molecules and chemical bonds.
    * Composition, structure & function of biomolecules.
    * Stabilizing interactions.
    * Principles of biophysical chemistry.
    * Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.
    * Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.
    * Conformation of proteins.
    * Conformation of nucleic acids.
    * Stability of protein and nucleic acid structures.
    * Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.


    2. CELLULAR ORGANIZATION
    * Membrane structure and function
    * Structural organization and function of intracellular organelles
    * Organization of genes and chromosomes
    * Cell division & cell cycle
    * Microbial Physiology


    3. FUNDAMENTAL PROCESSES
    * DNA replication, repair and recombination
    * RNA synthesis and processing
    * Protein synthesis and processing
    * Control of gene expression at transcription and translation level


    4. CELL COMMUNICATION & CELL SIGNALING
    * Host parasite interaction
    * Cell signaling
    * Cellular communication
    * Cancer
    * Innate and adaptive immune system


    DEVELOPMENTAL BIOLOGY
    * Basic concepts of development
    * Gametogenesis, fertilization and early development
    * Morphogenesis & organogenesis in animals
    * Morphogenesis and organogenesis in plants
    * Programmed cell death, aging and senescence.


    6. SYSTEM PHYSIOLOGY PLANT
    * Photosynthesis
    * Respiration & photorespiration
    * Nitrogen metabolism
    * Plant hormones
    * Sensory photobiology
    * Solute transport & photoassimilate translocation
    * Secondary metabolites
    * Stress physiology


    7. SYSTEM PHYSIOLOGY ANIMAL
    * Blood and circulation,
    * Cardiovascular System
    * Respiratory system
    * Nervous system
    * Sense organs
    * Excretory system
    * Thermoregulation
    * Stress and adaptation
    * Digestive system

  11. #11
    subodh1014 Array
    Join Date
    Jan 2012
    Posts
    593

    Re: Latest syllabus of Life Science for CSIR?

    hi,
    dear friend,
    the detailed and latest syllabus of CSIR is given as below:-

    The Joint CSIR-UGC JRF/LS (NET) Examination shall comprise 2 papers:

    PAPER I: duration: 2 ½ hours and maximum of 200 marks. 2 marks each question. (252752)

    Part -A: 40 General Science questions, attempt any 25 questions.

    Part -B: 100 questions, attempt any 75 questions.

    PAPER II: 2 ½ hours duration and shall have a maximum of 200 marks (2011512)

    This Paper shall consist of 39-45 short answer type questions requiring descriptive answers. Answer each question, on one page.

    There shall be one compulsory question of twenty Marks. In addition to the compulsory question, the candidate is required to answer a maximum of 15 questions of twelve marks each.



    SYLLABUS FOR PAPER I AND II



    1. MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY



    1. Structure of atoms, molecules and chemical bonds.

    1. Composition, structure & function of biomolecules (carbohydrates, lipids, proteins, N.Acids and vitamins).

    1. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding, hydrophobic interaction, etc.).

    1. Principles of biophysical chemistry (pH, buffer, reaction kinetics, thermodynamics, colligative properties).

    1. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.

    1. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.

    1. Conformation of proteins (Ramachandran plot, 20, 30 & 40 structures; domains; motif and folds).

    1. Conformation of nucleic acids (A-, B-, Z-, DNA), t-RNA, micro-RNA).

    1. Stability of protein and nucleic acid structures.

    1. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.



    2. CELLULAR ORGANIZATION



    1. Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting & regulation of intracellular transport, electrical properties of membranes.

    1. Structural organization and function of intracellular organelles: Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, ER , peroxisomes, plastids, vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility.

    1. Organization of genes and chromosomes: Operon, interrupted genes, gene families, structure of chromatin and chromosomes, unique and repetitive DNA, heterochromatin, euchromatin, transposons.

    1. Cell division & cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle.

    1. Microbial Physiology: Growth, yield & characteristics, strategies of cell division, stress response.

    3. FUNDAMENTAL PROCESSES

    1. DNA replication, repair and recombination: Unit of replication, enzymes involved, replication origin and replication fork, fidelity of replication, extrachromosomal replicons, and DNA damage and repair mechanisms.

    1. RNA synthesis and processing: Transcription factors and machinery, formation of initiation complex, transcription activators and repressors, RNA polymerases, capping, elongation & termination, RNA processing, RNA editing, splicing, polyadenylation, structure and function of different types of RNA, RNA transport.

    1. Protein synthesis and processing: Ribosome, formation of initiation complex, initiation factors and their regulation, elongation and elongation factors, termination, genetic code, aminoacylation of tRNA, tRNA-identity, aminoacyl tRNA synthetase, translational proof-reading, translational inhibitors, post- translational modification of proteins.

    1. Control of gene expression at transcription and translation level: Regulation of phages, viruses, prokaryotic and eukaryotic gene expression, role of chromatin in regulating gene expression and gene silencing.



    4. CELL COMMUNICATION & CELL SIGNALING



    1. Host parasite interaction: Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells.

    1. Cell signaling: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component signaling systems, bacterial chemotaxis and quorum sensing.

    1. Cellular communication: Regulation of hema topoiesis, general principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins, neurotransmission and its regulation.

    1. Cancer: Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.

    1. Innate and adaptive immune system: Cells & molecules involved in innate and adaptive immunity, antigens, antigenicity and immunogenicity. B and T cell epitopes, structure & function of antibody molecules, generation of antibody diversity, monoclonal antibodies, antibody engineering, antigen-antibody interactions, MHC molecules, antigen processing & presentation, activation and differentiation of B & T cells, B and T cell receptors, humoral & cell-mediated immune responses, primary & secondary immune modulation, the complement system, Toll-like receptors, cell-mediated effector functions, inflammation, hypersensitivity & autoimmunity, immune response during bacterial (tuberculosis), parasitic (malaria) & viral (HIV) infections, congenital and acquired immunodeficiencies, vaccines.



    5. DEVELOPMENTAL BIOLOGY



    1. Basic concepts of development: Potency, commitment, specification, induction, competence, determination & differentiation; morphogenetic gradients; cell fate & cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; imprinting; mutants & transgenics in analysis of development.

    1. Gametogenesis, fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animals; embryo sac development & double fertilization in plants; zygote formation, cleavage, blastula formation, embryonic fields, gastrulation & formation of germ layers in animals; embryogenesis, establishment of symmetry in plants; seed formation & germination.

    1. Morphogenesis & organogenesis in animals: Cell aggregation & differentiation in Dictyostelium; axes and pattern formation in Drosophila, amphibia and chick; organogenesis – vulva formation in Caenorhabditis elegans; eye lens induction, limb development & regeneration in vertebrates; differentiation of neurons, post embryonic development-larval formation, metamorphosis; environmental regulation of normal development; sex determination.

    1. Morphogenesis and organogenesis in plants: Organization of shoot and root apical meristem; shoot and root development; leaf development and phyllotaxy; transition to flowering, floral meristems and floral development in Arabidopsis and Antirrhinum.

    1. Programmed cell death, aging and senescence.

    6. SYSTEM PHYSIOLOGY PLANT



    1. Photosynthesis: LH complexes; mechanisms of ETC; photoprotective mechanisms; CO2 fixation-C3, C4 CAM pathways.

    1. Respiration & photorespiration: TCA cycle; plant mitochondrial ET & ATP synthesis; alternate oxidase; photorespiration.

    1. Nitrogen metabolism: Nitrate and ammonium assimilation; amino acid biosynthesis.

    1. Plant hormones: Biosynthesis, storage, breakdown and transport; physiological effects and mechanisms of action.

    1. Sensory photobiology: Structure, function & mechanisms of action of phytochromes, cryptochromes & phototropins; stomatal movement; photoperiodism and biological clocks.

    1. Solute transport & photoassimilate translocation: Uptake, transport & translocation of water, ions, solutes & macromolecules from soil, through cells, across membranes, through xylem & phloem; transpiration; mechanisms of loading & unloading of photoassimilates.

    1. Secondary metabolites: Biosynthesis of terpenes, phenols and nitrogenous compounds and their roles.

    1. Stress physiology: Responses of plants to biotic (pathogen and insects) and abiotic (water, temperature and salt) stresses; mechanisms of resistance to biotic stress and tolerance to abiotic stress



    7. SYSTEM PHYSIOLOGY ANIMAL



    1. Blood and circulation: Blood corpuscles, haemopoiesis and formed elements, plasma function, blood volume, blood volume regulation, blood groups, haemoglobin, immunity, haemostasis.

    1. Cardiovascular System: Comparative anatomy of heart structure, myogenic heart, specialized tissue, ECG – its principle and significance, cardiac cycle, heart as a pump, blood pressure, neural and chemical regulation of all above.

    1. Respiratory system: Comparison of respiration in different species, anatomical considerations, transport of gases, exchange of gases, waste elimination, neural and chemical regulation of respiration.

    1. Nervous system: Neurons, action potential, gross neuroanatomy of the brain and spinal cord, central and peripheral nervous system, neural control of muscle tone and posture.

    1. Sense organs: Vision, hearing and tactile response.

    1. Excretory system: Comparative physiology of excretion, kidney, urine formation, urine concentration, waste elimination, micturition, regulation of water balance, blood volume, blood pressure, electrolyte balance, acid-base balance.

    1. Thermoregulation: Comfort zone, body temperature – physical, chemical, neural regulation, acclimatization.

    1. Stress and adaptation

    <>I.Digestive system: Digestion, absorption, energy balance, BMR. The Joint CSIR-UGC JRF/LS (NET) Examination shall comprise 2 papers:

    PAPER I: duration: 2 ½ hours and maximum of 200 marks. 2 marks each question. (252752)

    Part -A: 40 General Science questions, attempt any 25 questions.

    Part -B: 100 questions, attempt any 75 questions.

    PAPER II: 2 ½ hours duration and shall have a maximum of 200 marks (2011512)

    This Paper shall consist of 39-45 short answer type questions requiring descriptive answers. Answer each question, on one page.

    There shall be one compulsory question of twenty Marks. In addition to the compulsory question, the candidate is required to answer a maximum of 15 questions of twelve marks each.



    SYLLABUS FOR PAPER I AND II



    1. MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY



    1. Structure of atoms, molecules and chemical bonds.

    1. Composition, structure & function of biomolecules (carbohydrates, lipids, proteins, N.Acids and vitamins).

    1. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding, hydrophobic interaction, etc.).

    1. Principles of biophysical chemistry (pH, buffer, reaction kinetics, thermodynamics, colligative properties).

    1. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.

    1. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.

    1. Conformation of proteins (Ramachandran plot, 20, 30 & 40 structures; domains; motif and folds).

    1. Conformation of nucleic acids (A-, B-, Z-, DNA), t-RNA, micro-RNA).

    1. Stability of protein and nucleic acid structures.

    1. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.



    2. CELLULAR ORGANIZATION



    1. Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting & regulation of intracellular transport, electrical properties of membranes.

    1. Structural organization and function of intracellular organelles: Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, ER , peroxisomes, plastids, vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility.

    1. Organization of genes and chromosomes: Operon, interrupted genes, gene families, structure of chromatin and chromosomes, unique and repetitive DNA, heterochromatin, euchromatin, transposons.

    1. Cell division & cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle.

    1. Microbial Physiology: Growth, yield & characteristics, strategies of cell division, stress response.

    3. FUNDAMENTAL PROCESSES

    1. DNA replication, repair and recombination: Unit of replication, enzymes involved, replication origin and replication fork, fidelity of replication, extrachromosomal replicons, and DNA damage and repair mechanisms.

    1. RNA synthesis and processing: Transcription factors and machinery, formation of initiation complex, transcription activators and repressors, RNA polymerases, capping, elongation & termination, RNA processing, RNA editing, splicing, polyadenylation, structure and function of different types of RNA, RNA transport.

    1. Protein synthesis and processing: Ribosome, formation of initiation complex, initiation factors and their regulation, elongation and elongation factors, termination, genetic code, aminoacylation of tRNA, tRNA-identity, aminoacyl tRNA synthetase, translational proof-reading, translational inhibitors, post- translational modification of proteins.

    1. Control of gene expression at transcription and translation level: Regulation of phages, viruses, prokaryotic and eukaryotic gene expression, role of chromatin in regulating gene expression and gene silencing.



    4. CELL COMMUNICATION & CELL SIGNALING



    1. Host parasite interaction: Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells.

    1. Cell signaling: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component signaling systems, bacterial chemotaxis and quorum sensing.

    1. Cellular communication: Regulation of hema topoiesis, general principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins, neurotransmission and its regulation.

    1. Cancer: Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.

    1. Innate and adaptive immune system: Cells & molecules involved in innate and adaptive immunity, antigens, antigenicity and immunogenicity. B and T cell epitopes, structure & function of antibody molecules, generation of antibody diversity, monoclonal antibodies, antibody engineering, antigen-antibody interactions, MHC molecules, antigen processing & presentation, activation and differentiation of B & T cells, B and T cell receptors, humoral & cell-mediated immune responses, primary & secondary immune modulation, the complement system, Toll-like receptors, cell-mediated effector functions, inflammation, hypersensitivity & autoimmunity, immune response during bacterial (tuberculosis), parasitic (malaria) & viral (HIV) infections, congenital and acquired immunodeficiencies, vaccines.



    5. DEVELOPMENTAL BIOLOGY



    1. Basic concepts of development: Potency, commitment, specification, induction, competence, determination & differentiation; morphogenetic gradients; cell fate & cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; imprinting; mutants & transgenics in analysis of development.

    1. Gametogenesis, fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animals; embryo sac development & double fertilization in plants; zygote formation, cleavage, blastula formation, embryonic fields, gastrulation & formation of germ layers in animals; embryogenesis, establishment of symmetry in plants; seed formation & germination.

    1. Morphogenesis & organogenesis in animals: Cell aggregation & differentiation in Dictyostelium; axes and pattern formation in Drosophila, amphibia and chick; organogenesis – vulva formation in Caenorhabditis elegans; eye lens induction, limb development & regeneration in vertebrates; differentiation of neurons, post embryonic development-larval formation, metamorphosis; environmental regulation of normal development; sex determination.

    1. Morphogenesis and organogenesis in plants: Organization of shoot and root apical meristem; shoot and root development; leaf development and phyllotaxy; transition to flowering, floral meristems and floral development in Arabidopsis and Antirrhinum.

    1. Programmed cell death, aging and senescence.

    6. SYSTEM PHYSIOLOGY PLANT



    1. Photosynthesis: LH complexes; mechanisms of ETC; photoprotective mechanisms; CO2 fixation-C3, C4 CAM pathways.

    1. Respiration & photorespiration: TCA cycle; plant mitochondrial ET & ATP synthesis; alternate oxidase; photorespiration.

    1. Nitrogen metabolism: Nitrate and ammonium assimilation; amino acid biosynthesis.

    1. Plant hormones: Biosynthesis, storage, breakdown and transport; physiological effects and mechanisms of action.

    1. Sensory photobiology: Structure, function & mechanisms of action of phytochromes, cryptochromes & phototropins; stomatal movement; photoperiodism and biological clocks.

    1. Solute transport & photoassimilate translocation: Uptake, transport & translocation of water, ions, solutes & macromolecules from soil, through cells, across membranes, through xylem & phloem; transpiration; mechanisms of loading & unloading of photoassimilates.

    1. Secondary metabolites: Biosynthesis of terpenes, phenols and nitrogenous compounds and their roles.

    1. Stress physiology: Responses of plants to biotic (pathogen and insects) and abiotic (water, temperature and salt) stresses; mechanisms of resistance to biotic stress and tolerance to abiotic stress



    7. SYSTEM PHYSIOLOGY ANIMAL



    1. Blood and circulation: Blood corpuscles, haemopoiesis and formed elements, plasma function, blood volume, blood volume regulation, blood groups, haemoglobin, immunity, haemostasis.

    1. Cardiovascular System: Comparative anatomy of heart structure, myogenic heart, specialized tissue, ECG – its principle and significance, cardiac cycle, heart as a pump, blood pressure, neural and chemical regulation of all above.

    1. Respiratory system: Comparison of respiration in different species, anatomical considerations, transport of gases, exchange of gases, waste elimination, neural and chemical regulation of respiration.

    1. Nervous system: Neurons, action potential, gross neuroanatomy of the brain and spinal cord, central and peripheral nervous system, neural control of muscle tone and posture.

    1. Sense organs: Vision, hearing and tactile response.

    1. Excretory system: Comparative physiology of excretion, kidney, urine formation, urine concentration, waste elimination, micturition, regulation of water balance, blood volume, blood pressure, electrolyte balance, acid-base balance.

    1. Thermoregulation: Comfort zone, body temperature – physical, chemical, neural regulation, acclimatization.

    1. Stress and adaptation

    <>I.Digestive system: Digestion, absorption, energy balance, BMR. The Joint CSIR-UGC JRF/LS (NET) Examination shall comprise 2 papers:

    PAPER I: duration: 2 ½ hours and maximum of 200 marks. 2 marks each question. (252752)

    Part -A: 40 General Science questions, attempt any 25 questions.

    Part -B: 100 questions, attempt any 75 questions.

    PAPER II: 2 ½ hours duration and shall have a maximum of 200 marks (2011512)

    This Paper shall consist of 39-45 short answer type questions requiring descriptive answers. Answer each question, on one page.

    There shall be one compulsory question of twenty Marks. In addition to the compulsory question, the candidate is required to answer a maximum of 15 questions of twelve marks each.



    SYLLABUS FOR PAPER I AND II



    1. MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY



    1. Structure of atoms, molecules and chemical bonds.

    1. Composition, structure & function of biomolecules (carbohydrates, lipids, proteins, N.Acids and vitamins).

    1. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding, hydrophobic interaction, etc.).

    1. Principles of biophysical chemistry (pH, buffer, reaction kinetics, thermodynamics, colligative properties).

    1. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.

    1. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.

    1. Conformation of proteins (Ramachandran plot, 20, 30 & 40 structures; domains; motif and folds).

    1. Conformation of nucleic acids (A-, B-, Z-, DNA), t-RNA, micro-RNA).

    1. Stability of protein and nucleic acid structures.

    1. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.



    2. CELLULAR ORGANIZATION



    1. Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting & regulation of intracellular transport, electrical properties of membranes.

    1. Structural organization and function of intracellular organelles: Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, ER , peroxisomes, plastids, vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility.

    1. Organization of genes and chromosomes: Operon, interrupted genes, gene families, structure of chromatin and chromosomes, unique and repetitive DNA, heterochromatin, euchromatin, transposons.

    1. Cell division & cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle.

    1. Microbial Physiology: Growth, yield & characteristics, strategies of cell division, stress response.

    3. FUNDAMENTAL PROCESSES

    1. DNA replication, repair and recombination: Unit of replication, enzymes involved, replication origin and replication fork, fidelity of replication, extrachromosomal replicons, and DNA damage and repair mechanisms.

    1. RNA synthesis and processing: Transcription factors and machinery, formation of initiation complex, transcription activators and repressors, RNA polymerases, capping, elongation & termination, RNA processing, RNA editing, splicing, polyadenylation, structure and function of different types of RNA, RNA transport.

    1. Protein synthesis and processing: Ribosome, formation of initiation complex, initiation factors and their regulation, elongation and elongation factors, termination, genetic code, aminoacylation of tRNA, tRNA-identity, aminoacyl tRNA synthetase, translational proof-reading, translational inhibitors, post- translational modification of proteins.

    1. Control of gene expression at transcription and translation level: Regulation of phages, viruses, prokaryotic and eukaryotic gene expression, role of chromatin in regulating gene expression and gene silencing.



    4. CELL COMMUNICATION & CELL SIGNALING



    1. Host parasite interaction: Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells.

    1. Cell signaling: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component signaling systems, bacterial chemotaxis and quorum sensing.

    1. Cellular communication: Regulation of hema topoiesis, general principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins, neurotransmission and its regulation.

    1. Cancer: Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.

    1. Innate and adaptive immune system: Cells & molecules involved in innate and adaptive immunity, antigens, antigenicity and immunogenicity. B and T cell epitopes, structure & function of antibody molecules, generation of antibody diversity, monoclonal antibodies, antibody engineering, antigen-antibody interactions, MHC molecules, antigen processing & presentation, activation and differentiation of B & T cells, B and T cell receptors, humoral & cell-mediated immune responses, primary & secondary immune modulation, the complement system, Toll-like receptors, cell-mediated effector functions, inflammation, hypersensitivity & autoimmunity, immune response during bacterial (tuberculosis), parasitic (malaria) & viral (HIV) infections, congenital and acquired immunodeficiencies, vaccines.



    5. DEVELOPMENTAL BIOLOGY



    1. Basic concepts of development: Potency, commitment, specification, induction, competence, determination & differentiation; morphogenetic gradients; cell fate & cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; imprinting; mutants & transgenics in analysis of development.

    1. Gametogenesis, fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animals; embryo sac development & double fertilization in plants; zygote formation, cleavage, blastula formation, embryonic fields, gastrulation & formation of germ layers in animals; embryogenesis, establishment of symmetry in plants; seed formation & germination.

    1. Morphogenesis & organogenesis in animals: Cell aggregation & differentiation in Dictyostelium; axes and pattern formation in Drosophila, amphibia and chick; organogenesis – vulva formation in Caenorhabditis elegans; eye lens induction, limb development & regeneration in vertebrates; differentiation of neurons, post embryonic development-larval formation, metamorphosis; environmental regulation of normal development; sex determination.

    1. Morphogenesis and organogenesis in plants: Organization of shoot and root apical meristem; shoot and root development; leaf development and phyllotaxy; transition to flowering, floral meristems and floral development in Arabidopsis and Antirrhinum.

    1. Programmed cell death, aging and senescence.

    6. SYSTEM PHYSIOLOGY PLANT



    1. Photosynthesis: LH complexes; mechanisms of ETC; photoprotective mechanisms; CO2 fixation-C3, C4 CAM pathways.

    1. Respiration & photorespiration: TCA cycle; plant mitochondrial ET & ATP synthesis; alternate oxidase; photorespiration.

    1. Nitrogen metabolism: Nitrate and ammonium assimilation; amino acid biosynthesis.

    1. Plant hormones: Biosynthesis, storage, breakdown and transport; physiological effects and mechanisms of action.

    1. Sensory photobiology: Structure, function & mechanisms of action of phytochromes, cryptochromes & phototropins; stomatal movement; photoperiodism and biological clocks.

    1. Solute transport & photoassimilate translocation: Uptake, transport & translocation of water, ions, solutes & macromolecules from soil, through cells, across membranes, through xylem & phloem; transpiration; mechanisms of loading & unloading of photoassimilates.

    1. Secondary metabolites: Biosynthesis of terpenes, phenols and nitrogenous compounds and their roles.

    1. Stress physiology: Responses of plants to biotic (pathogen and insects) and abiotic (water, temperature and salt) stresses; mechanisms of resistance to biotic stress and tolerance to abiotic stress



    7. SYSTEM PHYSIOLOGY ANIMAL



    1. Blood and circulation: Blood corpuscles, haemopoiesis and formed elements, plasma function, blood volume, blood volume regulation, blood groups, haemoglobin, immunity, haemostasis.

    1. Cardiovascular System: Comparative anatomy of heart structure, myogenic heart, specialized tissue, ECG – its principle and significance, cardiac cycle, heart as a pump, blood pressure, neural and chemical regulation of all above.

    1. Respiratory system: Comparison of respiration in different species, anatomical considerations, transport of gases, exchange of gases, waste elimination, neural and chemical regulation of respiration.

    1. Nervous system: Neurons, action potential, gross neuroanatomy of the brain and spinal cord, central and peripheral nervous system, neural control of muscle tone and posture.

    1. Sense organs: Vision, hearing and tactile response.

    1. Excretory system: Comparative physiology of excretion, kidney, urine formation, urine concentration, waste elimination, micturition, regulation of water balance, blood volume, blood pressure, electrolyte balance, acid-base balance.

    1. Thermoregulation: Comfort zone, body temperature – physical, chemical, neural regulation, acclimatization.

    1. Stress and adaptation

    <>I.Digestive system: Digestion, absorption, energy balance, BMR.


    all the best for your future.....................

  12. #12
    param pita Array
    Join Date
    Feb 2012
    Posts
    301

    Re: Latest syllabus of Life Science for CSIR?

    Dear,national eligibility test which is conduct University grant commission twice in year

    1. Moleucules and their interaction relavent to biology

    2. Cellular organization
    Membrane structure and function
    Structural Organisation and function of intracellular organelles
    organization of genes and chromosomes
    Cell division and cell cycle
    Microbial Physiology

    3. Fundamental Process
    DNA replication, repair and recombination
    RNA synthesis and processing
    Protein synthesis and processing
    control of gene expression at transcription and translation level

    4.Cell Communication and Cell Signaling
    Host parasite Interaction
    Cell signaling
    Cellular communication
    Cancer
    Innate and adaptive immune system

    5. Development Biology
    basic concepts of development
    Gametogenesis, fertallization and early development
    morphogenesis and organogenesis in animals
    Morphogenesis and Organogenesis in plants

    6. System physiology-Plant
    Photosynthesis
    Respiration and Photorespiration
    Nitrogen Metabolism
    Plant Hormones
    Sensory Photobiology
    solute transport and photoassimilate translocation
    stree physiology
    SYLLABUS FOR PAPER I AND II



    1. MOLECULES & THEIR INTERACTION RELAVENT TO BIOLOGY


    1. Structure of atoms, molecules and chemical bonds.
    1. Composition, structure & function of biomolecules (carbohydrates, lipids, proteins, N.Acids and vitamins).
    1. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding, hydrophobic interaction, etc.).
    1. Principles of biophysical chemistry (pH, buffer, reaction kinetics, thermodynamics, colligative properties).
    1. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.
    1. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes.
    1. Conformation of proteins (Ramachandran plot, 20, 30 & 40 structures; domains; motif and folds).
    1. Conformation of nucleic acids (A-, B-, Z-, DNA), t-RNA, micro-RNA).
    1. Stability of protein and nucleic acid structures.
    1. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.


    2. CELLULAR ORGANIZATION


    1. Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting & regulation of intracellular transport, electrical properties of membranes.
    1. Structural organization and function of intracellular organelles: Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, ER , peroxisomes, plastids, vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility.
    1. Organization of genes and chromosomes: Operon, interrupted genes, gene families, structure of chromatin and chromosomes, unique and repetitive DNA, heterochromatin, euchromatin, transposons.
    1. Cell division & cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle.
    1. Microbial Physiology: Growth, yield & characteristics, strategies of cell division, stress response.
    3. FUNDAMENTAL PROCESSES
    1. DNA replication, repair and recombination: Unit of replication, enzymes involved, replication origin and replication fork, fidelity of replication, extrachromosomal replicons, and DNA damage and repair mechanisms.
    1. RNA synthesis and processing: Transcription factors and machinery, formation of initiation complex, transcription activators and repressors, RNA polymerases, capping, elongation & termination, RNA processing, RNA editing, splicing, polyadenylation, structure and function of different types of RNA, RNA transport.
    1. Protein synthesis and processing: Ribosome, formation of initiation complex, initiation factors and their regulation, elongation and elongation factors, termination, genetic code, aminoacylation of tRNA, tRNA-identity, aminoacyl tRNA synthetase, translational proof-reading, translational inhibitors, post- translational modification of proteins.
    1. Control of gene expression at transcription and translation level: Regulation of phages, viruses, prokaryotic and eukaryotic gene expression, role of chromatin in regulating gene expression and gene silencing.


    4. CELL COMMUNICATION & CELL SIGNALING


    1. Host parasite interaction: Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells.
    1. Cell signaling: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component signaling systems, bacterial chemotaxis and quorum sensing.
    1. Cellular communication: Regulation of hema topoiesis, general principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins, neurotransmission and its regulation.
    1. Cancer: Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.
    1. Innate and adaptive immune system: Cells & molecules involved in innate and adaptive immunity, antigens, antigenicity and immunogenicity. B and T cell epitopes, structure & function of antibody molecules, generation of antibody diversity, monoclonal antibodies, antibody engineering, antigen-antibody interactions, MHC molecules, antigen processing & presentation, activation and differentiation of B & T cells, B and T cell receptors, humoral & cell-mediated immune responses, primary & secondary immune modulation, the complement system, Toll-like receptors, cell-mediated effector functions, inflammation, hypersensitivity & autoimmunity, immune response during bacterial (tuberculosis), parasitic (malaria) & viral (HIV) infections, congenital and acquired immunodeficiencies, vaccines.


    5. DEVELOPMENTAL BIOLOGY


    1. Basic concepts of development: Potency, commitment, specification, induction, competence, determination & differentiation; morphogenetic gradients; cell fate & cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; imprinting; mutants & transgenics in analysis of development.
    1. Gametogenesis, fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animals; embryo sac development & double fertilization in plants; zygote formation, cleavage, blastula formation, embryonic fields, gastrulation & formation of germ layers in animals; embryogenesis, establishment of symmetry in plants; seed formation & germination.
    1. Morphogenesis & organogenesis in animals: Cell aggregation & differentiation in Dictyostelium; axes and pattern formation in Drosophila, amphibia and chick; organogenesis – vulva formation in Caenorhabditis elegans; eye lens induction, limb development & regeneration in vertebrates; differentiation of neurons, post embryonic development-larval formation, metamorphosis; environmental regulation of normal development; sex determination.
    1. Morphogenesis and organogenesis in plants: Organization of shoot and root apical meristem; shoot and root development; leaf development and phyllotaxy; transition to flowering, floral meristems and floral development in Arabidopsis and Antirrhinum.
    1. Programmed cell death, aging and senescence.
    6. SYSTEM PHYSIOLOGY PLANT


    1. Photosynthesis: LH complexes; mechanisms of ETC; photoprotective mechanisms; CO2 fixation-C3, C4 CAM pathways.
    1. Respiration & photorespiration: TCA cycle; plant mitochondrial ET & ATP synthesis; alternate oxidase; photorespiration.
    1. Nitrogen metabolism: Nitrate and ammonium assimilation; amino acid biosynthesis.
    1. Plant hormones: Biosynthesis, storage, breakdown and transport; physiological effects and mechanisms of action.
    1. Sensory photobiology: Structure, function & mechanisms of action of phytochromes, cryptochromes & phototropins; stomatal movement; photoperiodism and biological clocks.
    1. Solute transport & photoassimilate translocation: Uptake, transport & translocation of water, ions, solutes & macromolecules from soil, through cells, across membranes, through xylem & phloem; transpiration; mechanisms of loading & unloading of photoassimilates.
    1. Secondary metabolites: Biosynthesis of terpenes, phenols and nitrogenous compounds and their roles.
    1. Stress physiology: Responses of plants to biotic (pathogen and insects) and abiotic (water, temperature and salt) stresses; mechanisms of resistance to biotic stress and tolerance to abiotic stress



  13. #13
    Unregistered

    Re: Latest syllabus of Life Science for CSIR?

    tips for preparing csir net exam and tel the referance books plzz

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